Karen Buchkovich, Ph.D.
Instructor - Montgomery County Community College

Karen Buchkovich, Ph.D.

Montgomery County Community College

West Campus

101 College Drive

Pottstown, PA 19464

 

Office:   South Hall, Room 228, Cube #3

Phone: 610-769-1969

 

 

Current Courses

Microbiology and Immunology (BIO 140)

 

Previous Course

Biology

Microbiology

Biology of Cancer (senior seminar)

Education

Ph.D., Molecular Microbiology, State University of New York at Stony Brook        

> Dissertation research at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

B.S., Molecular and Cell Biology, Pennsylvania State University          

 

 

Research Interests

Viral control of cell doubling, viral regulation of tumor suppressor proteins, viral oncogenesis.

Telomere and telomerase regulation of cell doubling and response to DNA damage.

 

 

 Selected Publications

 

  1. JPMorgan  breaking news, monthly, and quarterly reports on biotechnology companies (DCGN, EXEL, MAXY, DVSA), chemical companies (DD, NZYMB, CBM), and agricultural companies (Monsanto, Dupont). (2002-2008)

  2. Miknyoczki SJ , Wan W , Chang H , Dobrzanski P , Ruggeri BA , Dionne CA , and Buchkovich K . (2002). The neurotrophin -trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice. Clin. Cancer Res. 8, 1924-31.

  3. Buchkovich, K.J. and Greider, C.W. (1996).   Telomerase Regulation During Entry into the Cell Cycle in Normal Human T cells, Mol. Biol. Cell, 7, 1443-1454.

  4. Buchkovich, K.J. (1996).   Telomeres, telomerase, and the cell cycle.   In Progress in Cell Cycle Research, Volume 2 (eds, Meijer, L. and Guidet, S., Plenum Press, New York, NY), pp. 187-195.

  5. Buchkovich, K. and Ziff E. (1994).   Nerve Growth Factor Regulates the Expression and Activity of p33cdk2 and p34cdc2 kinases in PC12 Pheochromocytoma Cells.   Mol. Biol. Cell 5, 1225-1241.

  6. Hu, Q., Lees, J., Buchkovich, K., and Harlow, E. (1992).   The Retinoblastoma Protein Physically Associates with the Human cdc2 Kinase.   Mol. Cell. Biol., 12, 971-980.

  7. Lees, J.A., Buchkovich, K., Marshak, D.R., Anderson, C.W., and Harlow, E. (1991).   The Retinoblastoma Protein is Phosphorylated on Multiple Sites by Human cdc2.   EMBO J. 10, 4279-4290.

  8. Horowitz, J.M., Yandell, D.W., Park, S.H., Canning, S., Whyte, P., Buchkovich, K., Harlow, E. Weinberg, R.A., and Dryja, T.P. (1989).   Point Mutational Inactivation of the Retinoblastoma Anti-oncogene.   Science 243, 937-940.

  9. Buchkovich, K., Duffy, L.A., and Harlow, E. (1989).   The Retinoblastoma Protein is Phosphorylated during Specific Phases of the Cell Cycle.   Cell 58, 1097-1105.

  10. Buchkovich, K., Dyson, N., Whyte, P., and Harlow, E. (1989).   Cellular Proteins Implicated in Transformation of Adenovirus and Other DNA Tumor Viruses.   In Common Mechanisms of Transformation by Small DNA Tumor Viruses, (ed. L.P. Villareal, American Society for Microbiology, Washington, D.C., U.S.A.), p. 262-278.

  11. Whyte, P., Buchkovich, K.J., Horowitz, J.M., Friend, S.H., Raybuck, M., Weinberg, R.A., and Harlow, E. (1988).   Association Between an Oncogene and an Anti-oncogene:   the Adenovirus E1A Proteins bind to the Retinoblastoma Gene Product.   Nature 334, 124-129.